Buildings with plan irregularity are commonly encountered when there is a scope for maximum utilization of the minimum available space. Also, these buildings respond differently when located in various seismic zones. One of the major problems associated with irregular buildings is torsion. It also leads to difference in the stress induced in different wings of the building leading to stress concentration at the re-entrant corner. This study focuses on the response of the building with a re-entrant corner located in various soils. The major objective is to study the response of a C, H, L and T shape building in different soil at seismic zone IV and also, to compare the buildings containing re-entrant corners with a building of regular plan configuration by performing linear dynamic analysis. While modeling, the plan area of all the models has been made equal in order to facilitate comparison. The results obtained are compared for different soil stratum in terms of storey drift, base shear, and storey displacement. Along with this, the acceleration and time period also studied. When the re-entrant building was compared with regular building, it was observed that the former undergoes larger storey displacement and drift than the latter. Buildings with re-entrant corner are more vulnerable to seismic damages and are susceptible to earthquake corresponding to time periods of lower order; hence, the building plan must be of regular configuration in order to possess significant seismic resistance.