The buildings are present in sloping ground are very different from those in plain ground, in sloping ground the buildings are very irregular and unsymmetrical in horizontal and vertical planes. The buildings in sloping ground causes more damage during earthquake, because in sloping ground the structure is constructed with different column heights. In this study 3D analytical model of 10 storied building, the plan of each configuration includes 4 bays in Y direction and 6 bays in X direction which is kept same for all configurations of building frame, the slope chosen in between 0 to 30 degree. The building is located on seismic zone V, with different soil type; the models are analyzed and designed by ETABS 2015 software. Seismic analysis done by linear dynamic analysis (RSA). I concluded that the effect soil is more important on the earthquake performance of structure. As the soil stiffness increase the building performance increase by earthquake loads, the study also possess that in response spectrum analysis the performance of the building in sloping ground is more danger to earthquake than that of building present in plain ground.